Rheumatology

a) Describe the functional anatomy of temporomandibular (TM) joint. [3] b) What are the various TM joint disorders? [2.5] c) How to assess for TM joint involvement? [2.5] d) How to treat TM joint involvement in arthritis? [2]

a) What are the characteristic histopathologic findings in juvenile dermatomyositis (JDM)? [3] b) Discuss the common antibodies found in JDM and their clinical associations. [4] c) What are the management strategies for calcinosis? [3]

a) Describe the pathogenesis of drug-induced lupus. [4] b) Write clinical manifestations of drug-induced lupus. [2] c) Enumerate differences between drug-induced lupus and systemic lupus erythematosus. [2] d) Write laboratory features of drug induced lupus. [2]

a) Write the differences between autoimmune and autoinflammatory disorders. [2] b) Describe the mutations in monogenic autoinflammatory diseases with examples. [4] c) Describe the clinical features and treatment of syndrome with deficiency of adenosine deaminase. [4]

a) Discuss the immunopathogenesis of sarcoidosis. [4] b) Describe the musculoskeletal involvement in sarcoidosis. [4] c) How does early-onset childhood sarcoidosis differ from adult onset sarcoidosis? [2]

a) What do you understand by Artificial Intelligence? [4] b) Discuss the potential applications of Artificial Intelligence in Rheumatology. [6]

a) Describe the role of Tyrosine Kinase 2 (Tyk2) in cytokine signaling pathways. [4] b) Mention the potential uses and adverse effects of Tyk2 inhibitors. [3+3]

a) What is the role of occupational therapy in the management of rheumatic diseases? [2] b) Discuss the role of yoga in management of rheumatic diseases. [2] c) Describe the goals of exercise prescription in rheumatic diseases. [3] d) What are the various types of exercise? Give examples of each. [3]

a) Discuss the pathogenesis of connective tissue disease associated interstitial lung disease (CTD-ILD). [4] b) Write the risk factors for scleroderma-ILD. [2] c) Write assessment and current evidence based treatment modalities for scleroderma-ILD. [4]

a) Describe IL-18 biology and its role in inflammatory diseases. [3+3] b) What are the potential roles of targeting IL-18 in Rheumatology? [4]